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High-level description

This file contains unit tests for the Cas9-based lineage tracing data simulator in the Cassiopeia package. It tests various aspects of the simulator, including basic setup, error handling, and data generation functionality.

Code Structure

The main class TestCas9LineageTracingDataSimulator contains multiple test methods that check different aspects of the Cas9LineageTracingDataSimulator class. The tests cover basic setup, error handling, and data generation functionality.

Symbols

TestCas9LineageTracingDataSimulator

Description

A unittest.TestCase class that contains test methods for the Cas9LineageTracingDataSimulator.

Internal Logic

The class sets up a basic tree structure and several instances of Cas9LineageTracingDataSimulator with different configurations in the setUp method. It then tests various aspects of the simulator in separate test methods.

setUp

Description

Sets up the test environment by creating a basic tree structure and initializing several Cas9LineageTracingDataSimulator instances with different configurations.

test_basic_setup

Description

Tests the basic setup of the Cas9LineageTracingDataSimulator, including the number of characters, mutation rates, and priors.

test_setup_errors

Description

Tests various error conditions in the setup of Cas9LineageTracingDataSimulator, such as invalid input parameters.

test_get_cassettes

Description

Tests the get_cassettes method of the Cas9LineageTracingDataSimulator.

test_introduce_states

Description

Tests the introduce_states method of the Cas9LineageTracingDataSimulator.

test_silence_cassettes

Description

Tests the silence_cassettes method of the Cas9LineageTracingDataSimulator.

test_collapse_sites

Description

Tests the collapse_sites method of the Cas9LineageTracingDataSimulator.

test_simulator_basic

Description

Tests the basic functionality of the Cas9LineageTracingDataSimulator by overlaying data on a tree and checking the resulting character matrix.

test_no_collapse

Description

Tests the Cas9LineageTracingDataSimulator without collapsing sites.

test_no_resection

Description

Tests the Cas9LineageTracingDataSimulator without resection.

test_simulator_with_state_generating_distribution

Description

Tests the Cas9LineageTracingDataSimulator with a state-generating distribution.

test_simulator_with_per_character_priors

Description

Tests the Cas9LineageTracingDataSimulator with per-character priors.

test_simulator_with_per_character_rates

Description

Tests the Cas9LineageTracingDataSimulator with per-character mutation rates.

Dependencies

  • unittest
  • networkx
  • numpy
  • pandas
  • cassiopeia

Error Handling

The test methods use assertions to check for expected behavior and raise exceptions for unexpected results.

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